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These results suggest that let - 7a , miR - 16 , miR - 21 , miR - 29 and miR - 200c are the downstream targets of NF - B that are involved in NF - B -mediated inflammation

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Furthermore, principal coordinate analysis suggest a clear transition of oral microbiome from healthy smokeless tobacco non-consumers to OSCC oral tumor site samples with healthy smokeless tobacco consumers samples, and the contralateral buccal site of OSCC samples showed intermediate values with a significant overlap